By Health Publica Icon Health Publications
This can be a 3-in-1 reference publication. It offers a whole scientific dictionary overlaying hundreds of thousands of phrases and expressions on the subject of Down syndrome. It additionally offers vast lists of bibliographic citations. eventually, it presents details to clients on find out how to replace their wisdom utilizing a variety of web assets. The e-book is designed for physicians, clinical scholars getting ready for Board examinations, scientific researchers, and sufferers who are looking to get to grips with examine devoted to Down syndrome. in case your time is effective, this ebook is for you. First, you won't waste time looking the web whereas lacking loads of correct details. moment, the booklet additionally saves you time indexing and defining entries. eventually, you won't waste money and time printing hundreds and hundreds of websites.
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Additional info for Down Syndrome - A Medical Dictionary, Bibliography, and Annotated Research Guide to Internet References
In the second case-control study (DS compared to normal population), the plan is to investigate potential risk factors for DS, as epidemiologic investigations concerning the environmental aetiology of DS are limited. Specifically, the following risk factors, based on previous study findings, will be addressed: parental occupations and occupational exposures, parental smoking and alcohol use, prior use of specific contraceptives, family history of Alzheimer's disease, and parental preconception exposure to x-rays.
Second, they will create transgenic mice that transiently and specifically express elevated levels of Dyrk in the 36 Down Syndrome proliferative zone of the developing brain. Finally, they will analyze in detail the brains of these mice to ascertain whether reduction in the number of neuronal cells, or other defects reminiscent of Down Syndrome, have occurred as a result of Dyrk overexpression in the brain during the period of neurogenesis. Their transgenic mice may serve as a novel animal model to investigate the molecular basis of mental retardation in Down Syndrome.
Co-immunoprecipitation experiments will be done to identify interactions between the two receptors. All possible combinations will be tested. These experiments will begin to elucidate the specificity of the Dscam receptors for each other and their role in axon guidance. Generate_Screen • Project Title: AXON GIUDANCE AND TARGETING IN DROSOPHILA Principal Investigator & Institution: Zipursky, S L. , Suite 1200 Los Angeles, CA 90024 Timing: Fiscal Year 2001; Project Start 01-APR-2001; Project End 31-MAR-2006 Summary: (provided by applicant): Dscam is an axon guidance receptor that is required for the formation of neuronal connections in the Drosophila nervous system.
Down Syndrome - A Medical Dictionary, Bibliography, and Annotated Research Guide to Internet References by Health Publica Icon Health Publications