New PDF release: [Journal] Nature Chemical Biology. Volume 5. Number 4

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Extra info for [Journal] Nature Chemical Biology. Volume 5. Number 4

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PLoS Biol. 6, e239 (2008). 15. A. et al. J. Biol. Chem. 281, 22312–22320 (2006). 16. J. et al. J. Biol. Chem. 278, 7645–7654 (2003). 17. H. T. Curr. Biol. 13, 680–685 (2003). 18. , Chassaing, G. & Prochiantz, A. Trends Cell Biol. 8, 84–87 (1998). 19. J. J. Biophotonics Int. 11, 36–42 (2004). 219 ARTICLES Identification of a chemical probe for NAADP by virtual screening Edmund Naylor1,4, Abdelilah Arredouani1,4, Sridhar R Vasudevan1,4, Alexander M Lewis1, Raman Parkesh1, Akiko Mizote2, Daniel Rosen1, Justyn M Thomas1, Minoru Izumi2, A Ganesan3, Antony Galione1 & Grant C Churchill1 Research into the biological role of the Ca2+-releasing second messenger NAADP (nicotinic acid adenine dinucleotide phosphate) has been hampered by a lack of chemical probes.

Deconvoluting the functions of polypeptide N-αacetylgalactosaminyltransferase family members by glycopeptide substrate profiling. Chem. Biol. 11, 1009–1016 (2004). 78. A. & Jamison, O. Identification of common and unique peptide substrate preferences for the UDP-GalNAc: polypeptide α-Nacetylgalactosaminyltransferases T1 and T2 derived from oriented random peptide substrates. J. Biol. Chem. 281, 32403–32416 (2006). 79. DeFrees, S. et al. GlycoPEGylation of recombinant therapeutic proteins produced in Escherichia coli.

M. Note: Supplementary information and chemical compound information is available on the Nature Chemical Biology website. ACKNOWLEDGMENTS Our research was supported by a grant from the Biotechnology and Biological Sciences Research Council (grant number BB/D012694/1). We thank P. -C. Lee (University of Hong Kong) for providing ADP-ribosyl cyclase and C.

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[Journal] Nature Chemical Biology. Volume 5. Number 4


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